CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 46 enrolled
Drug / intervention
VR treatment for phantom limb painbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05296265
NCT05296265N/ACompleted

Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain: In-Person Treatment

Albert Einstein Healthcare Network·interventional·Posted Mar 25, 2022·Updated Oct 3, 2025

In Brief

A clinical study evaluating VR treatment for phantom limb pain for Phantom Limb Pain. Completed, enrolled 46 participants across 3 sites.

Detailed Summary

After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The proposed work will contrast the efficacy of two virtual reality treatments for phantom limb pain: a 'Distractor' and an Active VR treatment. In the Distractor treatment, participants are engaged in a visually immersive virtual reality experience that does not require leg movements (REAL i-Series® immersive VR experience). In the Active VR treatment, subjects play a series of VR games using the virtual rendering of both legs.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedMar 25, 2022
Enrollment StartMay 10, 2022
Primary CompletionMar 16, 2025
Study CompletionApr 6, 2025
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 4.3 years ago

Interventions

VR treatment for phantom limb painbehavioral

8 twice-weekly interventions of 1 hour; baseline, pre-intervention; immediately after the end of the in intervention; 1 week after the end of the intervention; 8 weeks after the end of the intervention