CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 200 enrolled
Drug / intervention
Peer-Delivered Behavioral Activation ("Peer Activate")behavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05299515
NCT05299515N/ACompleted
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Peer-Delivered Behavioral Activation Intervention to Improve Adherence to MT Among Low-Income, Minority Individuals With OUD

University of Maryland, College Park·interventional·Posted Mar 29, 2022·Updated Oct 27, 2025

In Brief

A clinical study evaluating Peer-Delivered Behavioral Activation ("Peer Activate") for Substance-Related Disorders and 6 related conditions. Completed, enrolled 200 participants across 2 sites.

Detailed Summary

The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) among low-income, minority individuals living with opioid use disorder (OUD) in Baltimore, Maryland. The intervention is based on behavioral activation (BA) and is specifically designed to be implemented by a trained peer recovery specialist. In this Type 1 hybrid effectiveness-implementation randomized controlled trial (RCT), we will evaluate the effectiveness and implementation of Peer Activate vs. treatment as usual (TAU) over six months.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSubstance-Related Disorders, Opioid Medication Assisted Treatment, Opioid Use Disorder, Opioid Use, Opioid Addiction, Treatment Adherence, Retention in Care
CountriesUnited States
CollaboratorsUniversity of Maryland, Baltimore, Henry Ford Health System

Timeline

N/ACompletedFinished
2023202420252026
First PostedMar 29, 2022
Enrollment StartApr 5, 2022
Primary CompletionSep 24, 2025
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 4.3 years ago

Interventions

Peer-Delivered Behavioral Activation ("Peer Activate")behavioral

The PRS-delivered Peer Activate intervention will consist of approximately four weekly "core" sessions (approximately 30 minutes-1 hour) with two additional sessions to reinforce core content, and then 6 optional "booster" sessions to reinforce skill practice. In Peer Activate sessions, participants will learn behavioral activation and problem-solving skills to assist in their retention and persistence in methadone treatment and incorporating value-driven, substance-free, rewarding activities into their daily life.