CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 48 enrolled
Drug / intervention
ALXN1910 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05307978
NCT05307978Phase 1Completed

A Phase 1, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study of Subcutaneously and Intravenously Administered ALXN1910 in Healthy Adult Participants

Alexion Pharmaceuticals, Inc.·interventional·Posted Apr 1, 2022·Updated Feb 27, 2025

In Brief

A Phase 1 clinical trial evaluating ALXN1910 and Placebo for Healthy. Completed, enrolled 48 participants across 1 site.

Detailed Summary

This is a Phase 1, randomized, double-blind, placebo-controlled study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of single ascending doses (SADs) of ALXN1910 subcutaneous (SC) and SAD of ALXN1910 intravenous (IV).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 1CompletedFinished
2023202420252026
First PostedApr 1, 2022
Enrollment StartApr 12, 2022
Primary CompletionFeb 7, 2023
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 4.3 years ago

Interventions

ALXN1910drug

Participants will receive a single dose of ALXN1910 IV or ALXN1910 SC according to their assigned cohort.

Placebodrug

Participants will receive Placebo IV or Placebo SC according to their assigned cohort.