CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Cigarettes with added sucroseother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05308316
NCT05308316N/ACompleted
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Impact of Sugars on Tobacco Product Toxicity and Abuse Liability

Masonic Cancer Center, University of Minnesota·interventional·Posted Apr 4, 2022·Updated Feb 27, 2026

In Brief

A clinical study evaluating Cigarettes with added sucrose for Tobacco Use. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The aim of this study is to investigate the impact of sugar levels in cigarette tobacco on cigarette abuse liability and appeal. Participants will attend several clinic visits to smoke cigarettes with different levels of sugars and will complete multiple questionnaires to assess their experiences. Each of the sessions will be separated by at least 48 hours but not more than 5 days. The hypothesis is that the measures collected in this study will indicate lower abuse liability for cigarettes with lowest sugar content.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTobacco Use
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

N/ACompletedFinished
2023202420252026
First PostedApr 4, 2022
Enrollment StartFeb 24, 2022
Primary CompletionOct 13, 2023
Study CompletionOct 9, 2025
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 4.2 years ago

Interventions

Cigarettes with added sucroseother

Winston brand cigarettes will be modified by adding sucrose to each cigarette at 2 levels so that the amount of total (originally present and added) sugar content in these cigarettes matches median and highest levels found in popular cigarette brands.