CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,134 enrolled
Drug / intervention
BNT162b2 +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05310084
NCT05310084Phase 3Completed

A PHASE 3, RANDOMIZED, OBSERVER-BLIND TRIAL TO EVALUATE THE SAFETY AND IMMUNOGENICITY OF BNT162b2 WHEN COADMINISTERED WITH SEASONAL INACTIVATED INFLUENZA VACCINE (SIIV) IN ADULTS 18 THROUGH 64 YEARS OF AGE

BioNTech SE·interventional·Posted Apr 4, 2022·Updated Jun 12, 2024

In Brief

A Phase 3 clinical trial evaluating BNT162b2, Placebo, and 1 other intervention for SARS-CoV-2 Infection and COVID-19. Completed, enrolled 1,134 participants across 26 sites in 2 countries.

Detailed Summary

This study will assess the safety and immunogenicity of a fourth dose (booster) of BNT162b2 when coadministered with SIIV compared to separate administration of the vaccines when given 1 month apart (SIIV followed by BNT162b2), in participants who have received 3 prior doses of 30 µg BNT162b2, with the third dose being at least 90 days before Visit 1 (Day 1). * Healthy adults 18 through 64 years of age will be randomized 1:1 to either the co-administration group, or the separate administration group * The duration of the study for each participant will be approximately 2 months * There are 3 scheduled study visits each about 1 month apart * The study will be conducted in New Zealand and Australia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, New Zealand
CollaboratorsPfizer

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedApr 4, 2022
Enrollment StartApr 20, 2022
Primary CompletionOct 5, 2022
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 4.2 years ago

Interventions

BNT162b2biological

Intramuscular injection

Placeboother

Saline intramuscular injection

Seasonal Inactivated Influenza Vaccinebiological

SIIV intramuscular injection