CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 162 enrolled
Drug / intervention
anesthesia approach (general anesthesia or non-general anesthesia)procedure
Likely dose
Not stated in record
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Search/NCT05315648
NCT05315648N/ACompleted

The Associations Between Perioperative Depression or Anxiety, Salivary Cortisol and α-amylase, and Administered Anesthesia Type in Knee Arthroscopy With Anterior Cruciate Ligament Reconstruction (ACLR): Prospective, Randomized Trial

Second Affiliated Hospital of Wenzhou Medical University·interventional·Posted Apr 7, 2022·Updated Jun 17, 2024

In Brief

A clinical study evaluating anesthesia approach (general anesthesia or non-general anesthesia) for Depression, Anxiety. Completed, enrolled 162 participants across 1 site.

Detailed Summary

Perioperative depression and/or anxiety play a critical role in patient presentation, satisfaction and outcomes. The aim of this study is to assess the level of perioperative depression and/or anxiety in patients with arthroscopic knee surgery and to evaluate their relationship with anesthesia approach (general anesthesia or non general anesthesia). The perioperative characteristic of depression or anxiety is assessed by Hospital Anxiety and Depression Scale (HADS) questionnaires and the level of salivary cortisol, salivary α-amylase (sAA) and blood glucose.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 7, 2022
Enrollment StartOct 20, 2021
Primary CompletionDec 31, 2023
Study CompletionJan 30, 2024
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 4.2 years ago

Interventions

anesthesia approach (general anesthesia or non-general anesthesia)procedure

patients in group GA received general anesthesia followed with FNB. patients in group NGA received CSEA followed with FNB