At a glance
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A Comparative Clinical Trial to Evaluate the Efficacy and Safety of Tacrolimus Versus Hydrocortisone in Treatment of Children With Atopic Dermatitis
In Brief
A Phase 4 clinical trial evaluating Tacrolimus and Hydrocortisone for Atopic and Dermatitis. Completed, enrolled 200 participants across 1 site.
Detailed Summary
Atopic dermatitis (AD) is a very common inflammatory, genetic skin disorder that occurs more frequently in children. Its exact etiology is not known but it is characterized by pruritic skin reactions with elevation in the levels of inflammatory markers. Corticosteroids are the first line and the mainstay therapy in management of atopic dermatitis but have many local and systemic adverse effects. The study aims to evaluate the efficacy and safety of topical tacrolimus ointment in comparison to topical hydrocortisone cream in management of children diagnosed with atopic dermatitis.
Study Details
Timeline
Interventions
0.03% topical tacrolimus ointment applied on the affected areas twice daily for 4 months.
1% hydrocortisone cream applied on the affected areas twice daily for 4 months.