CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 4,000 enrolled
Drug / intervention
Ultrasoundother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05326191
NCT05326191N/ACompleted
CompareCT.gov

First-trimester Placental Ultrasound Study (First PLUS): an Observational Cohort Study to Assess the Clinical Utility of the OxNNet Toolkit for the Prediction of Adverse Pregnancy Outcomes.

Perspectum·observational·Posted Apr 13, 2022·Updated Dec 15, 2023

In Brief

An observational study evaluating Ultrasound for Fetal Growth Complications and Pregnancy Complications. Completed, enrolled 4,000 participants across 1 site.

Detailed Summary

An observational cohort study to assess the clinical utility of the OxNNet Toolkit for the prediction of adverse pregnancy outcomes.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsFetal Growth Complications, Pregnancy Complications
CountriesUnited Kingdom
CollaboratorsUniversity of Oxford, Fetal Medicine Foundation

Timeline

N/ACompletedFinished
2023202420252026
First PostedApr 13, 2022
Enrollment StartMar 15, 2022
Primary CompletionNov 14, 2022
Study CompletionMay 30, 2023
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 4.2 years ago

Interventions

Ultrasoundother

All study interventions/procedures will happen during the participants routine clinic visit in which they will receive their routine Ultrasound scan, followed by an additional research scan, which will take approximately 2-3 minutes. A blood sample will also be taken from participants as part of their routine pregnancy care. Residual blood from the same sample will be used to conduct an additional test to quantify Placental Growth Factor (PlGF). Participants will also be asked questions about their relevant medical history and demographic data which is also routinely collected as part of their pregnancy record.