CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 20 enrolled
Drug / intervention
Pitocindrug
Likely dose
Pitocin 4mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05326776
NCT05326776Phase 2Completed
CompareCT.gov

Effect of Peripheral Oxytocin on Touch Pleasantness and Pain

University of California, San Diego·interventional·Posted Apr 14, 2022·Updated Dec 31, 2024

In Brief

A Phase 2 clinical trial evaluating Pitocin for Healthy Adults. Completed, enrolled 20 participants across 1 site.

Detailed Summary

Research shows that slow gentle skin stroking can activate special sensory nerves in the skin that elicit relaxing effects on the body and mind, similar to the effects of the hormone oxytocin. Studies also suggest that gentle stroking may even release oxytocin in the skin. However, we do not know what oxytocin does in the skin and how it affects nerves that send pleasant touch or pain signals to the brain. The proposed study will determine how individuals perceive gentle stroking and experimental pain before and after a skin injection of oxytocin compared to a placebo injection.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy Adults
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedApr 14, 2022
Enrollment StartApr 5, 2023
Primary CompletionAug 3, 2023
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 4.2 years ago

Interventions

Pitocindrug

At each session, 4mcg/2ml oxytocin or 2ml isotonic saline (0.9% sodium chloride; placebo control) will be injected into the middle of the dorsal forearm. Sessions will be separated by at least 48 hours to ensure drug clearance.