CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 12 enrolled
Drug / intervention
MK-2060drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05335005
NCT05335005Phase 1Completed

A Study to Evaluate Safety and Tolerability of Co-administration of MK-2060 and Clopidogrel in Participants With End-Stage Renal Disease on Hemodialysis

Merck Sharp & Dohme LLC·interventional·Posted Apr 19, 2022·Updated Oct 17, 2024

In Brief

A Phase 1 clinical trial evaluating MK-2060 for End-Stage Renal Disease and Kidney Failure, Chronic. Completed, enrolled 12 participants across 3 sites in 3 countries.

Detailed Summary

MK-2060 is being developed for prevention of thrombotic complications in end-stage renal disease (ESRD). The purpose of this study is to conduct a preliminary evaluation of the safety and tolerability of MK-2060 treatment in combination with a commonly used P2Y12 receptor inhibitor, clopidogrel, in ESRD patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIsrael, Romania, United States
Collaborators--

Timeline

Phase 1CompletedFinished
2023202420252026
First PostedApr 19, 2022
Enrollment StartMay 30, 2022
Primary CompletionFeb 14, 2023
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 4.2 years ago

Interventions

MK-2060drug

MK-2060 administered via IV infusion