CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 112 enrolled
Drug / intervention
Amoxicillin +2 moredrug
Likely dose
Amoxicillin 1 gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05342532
NCT05342532Phase 4Completed
CompareCT.gov

High-Dose Dual Therapy vs Standard Triple Therapy for Treatment-Naïve H. Pylori: A Prospective Randomized Control Trial in a Diverse Urban New York City Population

Icahn School of Medicine at Mount Sinai·interventional·Posted Apr 22, 2022·Updated Feb 1, 2023

In Brief

A Phase 4 clinical trial evaluating Amoxicillin, Omeprazole, and 1 other intervention for Helicobacter Pylori Infection. Completed, enrolled 112 participants across 1 site.

Detailed Summary

A phase 4 prospective, randomized, open-label clinical trial evaluating the efficacy of high dose dual therapy vs standard triple therapy in a diverse, urban New York City population.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHelicobacter Pylori Infection
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedApr 22, 2022
Enrollment StartJun 12, 2019
Primary CompletionJan 1, 2022
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 4.2 years ago

Interventions

Amoxicillindrug

1 g

Omeprazoledrug

40 mg. Patients were asked to take omeprazole one hour prior to food intake, while antibiotics were taken after meals.

Clarithromycindrug

500 mg twice daily