CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 300 enrolled
Drug / intervention
Anesthetic technique Propofol TIVA +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05346588
NCT05346588Phase 3Completed
CompareCT.gov

Feasibility Study for the Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia (THRIVE) Trial

Washington University School of Medicine·interventional·Posted Apr 26, 2022·Updated Nov 24, 2023

In Brief

A Phase 3 clinical trial evaluating Anesthetic technique Propofol TIVA and Anesthetic technique inhaled agent for Surgery--Complications and 11 related conditions. Completed, enrolled 300 participants across 4 sites.

Detailed Summary

To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSurgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Nausea, Postoperative, Anesthesia Morbidity, Depression, Sleep Disorders, Circadian Rhythm
CountriesUnited States
CollaboratorsUniversity of Michigan, University of Pennsylvania, Stanford University, Patient-Centered Outcomes Research Institute

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedApr 26, 2022
Enrollment StartSep 29, 2022
Primary CompletionApr 16, 2023
Study CompletionJun 28, 2023
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.2 years ago

Interventions

Anesthetic technique Propofol TIVAother

Propofol TIVA no inhaled agent

Anesthetic technique inhaled agentother

must administer inhaled agent.