CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 66 target
Drug / intervention
placeboother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05351333
NCT05351333N/AActiveUpdate OverdueUpdated 8mo ago · Completion was 11mo ago
Enrollment Stalled

Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation

Spaulding Rehabilitation Hospital·interventional·Posted Apr 28, 2022·Updated Oct 27, 2025

In Brief

A clinical study evaluating placebo for Spinal Cord Injuries and 2 related conditions. Active but no longer recruiting, targeting 66 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

The use of the conditioning open-label placebo (COLP) paradigm will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury. The goal is to provide the same level of pain relief with a reduced opioid intake to diminish side effects as well as the risk of addiction associated with opioid treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/AActive
2023202420252026
First PostedApr 28, 2022
Enrollment StartAug 3, 2022
Primary CompletionJul 31, 2025
Study CompletionJul 31, 2026
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 4.2 years ago

Interventions

placeboother

Sugar pill, with an essential-oil smell and of blue color used for conditioning.