CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 306 enrolled
Drug / intervention
New-prescription Alert +3 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05351749
NCT05351749N/ACompleted

Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use

University of Michigan·interventional·Posted Apr 28, 2022·Updated Mar 30, 2026

In Brief

A clinical study evaluating New-prescription Alert, New-prescription Alert with referral option, and 2 other interventions for Pulmonary Embolism and 2 related conditions. Completed, enrolled 306 participants across 1 site.

Detailed Summary

The researchers hypothesize that existing-prescription notifications directed to pharmacists are more likely to lead to a prescription change than existing-prescription notifications directed to prescribers. Furthermore, the researchers hypothesize that the availability of a pharmacist referral option is associated with a higher rate of prescription changes for initial-prescription alerts that are directed to the prescriber at the time of initial-prescribing errors. Findings from this project will establish a framework for implementing prescriber-pharmacist collaboration for high risk medications, including anticoagulants

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedApr 28, 2022
Enrollment StartAug 1, 2022
Primary CompletionDec 15, 2024
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 4.2 years ago

Interventions

New-prescription Alertbehavioral

An enhanced drug alert notification in the Michigan Medicine electronic health record (EHR) that is tailored to the specific type of inappropriate Direct Oral Anticoagulant (DOAC) use (e.g., dosing too high for renal dysfunction) and offers decision support to the prescriber to alter a newly prescribed DOAC prescription.

New-prescription Alert with referral optionbehavioral

An enhanced drug alert notification in the EHR that is tailored to the specific type of inappropriate DOAC use (e.g., dosing too high for renal dysfunction) and offers decision support to the prescriber to alter new DOAC prescription. This alert will ALSO include an option for referral to the anticoagulation clinic pharmacist for assistance.

Existing-prescription notification to prescriberbehavioral

Prescriber receives a notification through the EHR indicating an existing DOAC prescription may not be appropriate (e.g. due to renal function change, new drug-drug interactions), and recommending a prescription update.

Existing-prescription notification to pharmacistbehavioral

Pharmacist receives a notification through the EHR indicating an existing DOAC prescription may not be appropriate (e.g. due to renal function change, new drug-drug interactions), and recommending a prescription update.