CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 153 enrolled
Drug / intervention
TAK-062 +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05353985
NCT05353985Phase 2Completed

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of TAK-062 for the Treatment of Active Celiac Disease in Subjects Attempting a Gluten-Free Diet

Takeda·interventional·Posted Apr 29, 2022·Updated Aug 20, 2025

In Brief

A Phase 2 clinical trial evaluating TAK-062, Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bar, and 2 other interventions for Celiac Disease. Completed, enrolled 153 participants across 102 sites in 8 countries.

Detailed Summary

The main aim is to see how TAK-062 works to reduce celiac-related symptoms and improve small intestinal damage due to gluten exposure, in participants with celiac disease (CeD) attempting to maintain a gluten-free diet (GFD) in treated participants versus placebo controls.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCeliac Disease
CountriesBelgium, Canada, France, Italy, Poland, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedApr 29, 2022
Enrollment StartJun 30, 2022
Primary CompletionNov 6, 2024
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 4.2 years ago

Interventions

TAK-062drug

TAK-062 tablets.

Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bardietary

SIGE gluten bars.

TAK-062 Placebodrug

TAK-062 placebo-matching tablets.

Simulated Inadvertent Gluten Exposure (SIGE) Gluten-free Bardietary

SIGE gluten-free bars.