CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 138 target
Drug / intervention
STRICT LUNG +1 moreprocedure
Likely dose
Not stated in record
Key inclusion· 13
  • ✓Histologically or cytologically proven non-hematological cancer or known cancer with local progressive recurrence
  • ✓Age greater than 18 years
  • ✓Life expectancy greater than 6 months
  • ✓Maximum one central tumor ≤5 cm diameter or >1 adjacent tumors with summarized diameter ≤5 cm
Key exclusion· 7
  • ✕Tumor with intra-bronchial or intra-tracheal growth
  • ✕Previous radiotherapy with combined dose exceeding dose constraints at radiation site
  • ✕Cannot tolerate physical setup required for SBRT
  • ✕Uncontrolled intercurrent illness

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05354596
NCT05354596N/ARecruitingUpdate OverdueUpdated 39mo ago · Completion was 6mo ago
Enrollment Stalled
Long Recruiting
Update Overdue
CompareCT.gov

Stereotactic Radiation Therapy In Centrally Located Lung and Ultra-centrally Located Tumors in the Lung. STRICT-LUNG & STAR-LUNG STUDY

Rigshospitalet, Denmark·interventional·Posted Apr 29, 2022·Updated Mar 3, 2023

In Brief

A clinical study evaluating STRICT LUNG and STAR LUNG for Lung Cancer and 2 related conditions. Currently recruiting, targeting 138 participants across 6 sites.

Signals

Enrollment appears stalled

Detailed Summary

An open-label phase II study, investigating toxicity, treatment efficacy and the local tumor control rate in 69 patients with centrally located tumors and in 69 patients with ultra-centrally located tumors in the lung. Treatment and patient outcomes will be recorded. Centrally located tumors are treated on standard-linacs with daily CBCT image-guidance and plan adaptation. Ultra-centrally tumors are treated on MR-linacs with daily MR-guided plan-adaptation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLung Cancer, Metastases to Lung, Radiotherapy Side Effect
CountriesDenmark
CollaboratorsAarhus University Hospital, Odense University Hospital, Vejle Hospital, University of Copenhagen, Aalborg University Hospital

Timeline

N/ARecruiting
20232024202520262027202820292030203120322033
First PostedApr 29, 2022
Enrollment StartNov 1, 2022
Primary CompletionDec 30, 2025
Study CompletionMay 1, 2033
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 4.2 years ago

Interventions

STRICT LUNGprocedure

Stereotactic body radiation therapy: Centrally located tumors are treated on standard-linacs with daily CBCT image-guidance and plan adaptation.

STAR LUNGprocedure

Stereotactic body radiation therapy: Ultra-centrally tumors are treated on MR-linacs with daily MR-guided plan-adaptation.