At a glance
ClinicalIndex Comparison RecordN/ACompleted· 100 enrolled
Drug / intervention
20% Albumin +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Effect of Fluid Resuscitation with 20% Albumin Versus Crystalloid on the Microcirculation of Patients with Sepsis
In Brief
A clinical study evaluating 20% Albumin and Crystalloid for Sepsis, Severe and 2 related conditions. Completed, enrolled 100 participants across 1 site.
Detailed Summary
The sublingual microcirculation is impaired in sepsis and septic shock. Sidestream dark field imaging technology has been developed into a clinical tool to help the clinician assess the microcirculation at the bedside. The ideal resuscitation fluid has not been identified. The investigators aim to use this new bedside technology to establish the microcirculation properties of two popular resuscitation fluids.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSepsis, Severe, Sepsis, Septic Shock
CountriesIreland
CollaboratorsGrifols Biologicals, LLC
Timeline
N/ACompletedFinished
20222023202420252026
Enrollment StartSep 2021
First PostedMay 2022
Primary CompletionJul 2023
Study CompletionDec 2023
TodayJul 2026
First PostedMay 2, 2022
Enrollment StartSep 1, 2021
Primary CompletionJul 10, 2023
Study CompletionDec 1, 2023
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 4.2 years ago
Interventions
20% Albuminother
100ml boluses 20% Albumin
Crystalloidother
100ml bolus of crystalloid