CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 30 enrolled
Drug / intervention
Daxdilimabbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05368103
NCT05368103Phase 2Completed

A Phase 2A, Open Label, Proof of Concept Trial of Daxdilimab for the Treatment of Moderate To Severe Alopecia Areata

Amgen·interventional·Posted May 10, 2022·Updated Jan 7, 2025

In Brief

A Phase 2 clinical trial evaluating Daxdilimab for Alopecia Areata. Completed, enrolled 30 participants across 13 sites in 2 countries.

Detailed Summary

The purpose of this study is to assess the preliminary efficacy, safety, tolerability, PK, and PD of Daxdilimab in participants with moderate to severe AA, with ≥50% and ≤95% total scalp hair loss as defined by the SALT score at Screening and Day 1.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAlopecia Areata
CountriesCanada, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedMay 10, 2022
Enrollment StartApr 27, 2022
Primary CompletionAug 7, 2023
Study CompletionJan 26, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 4.1 years ago

Interventions

Daxdilimabbiological

Daxdilimab will be administered subcutaneously as two injections for each dose.