CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 25 enrolled
Drug / intervention
Sinemet Pill +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05369533
NCT05369533Phase 2Completed

Dopaminergic Enhancement of Rehabilitation Therapy Early After Stroke

University of California, Los Angeles·interventional·Posted May 11, 2022·Updated Mar 24, 2025

In Brief

A Phase 2 clinical trial evaluating Telerehabilitation, Sinemet Pill, and 1 other intervention for Stroke. Completed, enrolled 25 participants across 1 site.

Detailed Summary

This study explores the effects of telerehabilitation and a study medication on rehabilitation outcomes in patients with stroke resulting in arm weakness. Patients with arm weakness due to a stroke that happened in the past 30 days will be randomized into one of three groups: \[1\] TR and placebo (a sugar pill) on top of usual care; \[2\] TR and a medication (Sinemet 25/100) on top of usual care; \[3\] or usual care alone (no TR and no pill, but people in this group will be offered TR once the study is done). TR consists of 70 minutes/day of activities targeting arm function, 6 days a week for 6 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedMay 11, 2022
Enrollment StartAug 1, 2022
Primary CompletionMar 11, 2024
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 4.1 years ago

Interventions

Telerehabilitationdevice

The telerehabilitation system will deliver rehabilitation treatment sessions via a secured internet-connected computer. TR sessions will be a combination of games, exercises, stroke education, assessments, in addition to videoconferencing with therapists to discuss progress, issues, goals, and changes to the treatment plan.

Sinemet Pilldrug

Sinemet 25/100 will be taken 1 hour prior to TR, for the first 18 sessions.

Placebodrug

Placebo will be taken 1 hour prior to TR, for the first 18 sessions.