CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 43 enrolled
Drug / intervention
Myofunctional therapy (MT) nozzle +1 moredevice
Likely dose
Myofunctional therapy water bottle nozzle used daily with tongue suction, tongue press, and swallow exercisesAI-extracted
Key inclusion· 5
  • Mild to moderate obstructive sleep apnea (AHI 5–29 events/hour) confirmed within the last 2 years by in-lab polysomnography or home sleep apnea test
  • Ownership of a smartphone and willingness to use an app to log daily water intake
  • Willing to discontinue current OSA treatment for at least 3 days prior to testing
  • Age ≥18 years
Key exclusion· 8
  • Significant weight change (≥10% change in body weight in kg) since OSA diagnosis
  • Persistent excessive daytime sleepiness (Epworth Sleepiness Scale >10) despite OSA treatment
  • Medical comorbidities requiring fluid restriction (decompensated heart failure, end-stage renal disease, end-stage liver disease, hyponatremia [Na <130 mg/dL], or nocturia >7 times/night)
  • Significant psychiatric comorbidities including psychogenic polydipsia, obsessive-compulsive behavior, current suicidal ideation, or uncontrolled anxiety

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05371509
NCT05371509N/ACompleted

Novel Myofunctional Water Bottle to Reduce OSA and Snoring Study

Mayo Clinic·interventional·Posted May 12, 2022·Updated Nov 10, 2025

In Brief

A clinical study evaluating Myofunctional therapy (MT) nozzle and Placebo nozzle for Obstructive Sleep Apnea and Snoring. Completed, enrolled 43 participants across 1 site.

Detailed Summary

This research study is being done to determine whether the repetition and resistance from the daily use of the myofunctional therapy (MT) nozzle will improve obstructive sleep apnea and primary snoring.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedMay 12, 2022
Enrollment StartSep 7, 2023
Primary CompletionDec 10, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 4.1 years ago

Interventions

Myofunctional therapy (MT) nozzledevice

Water bottle nozzle designed to allow the user to repeatedly perform the tongue suction, tongue press, and swallow exercise movements while also providing targeted resistance to train and improve tongue, soft palate, and pharyngeal muscle strength and endurance.

Placebo nozzleother

The placebo bottle nozzle will look similar to the MT nozzle; but is not expected to function the same as the MT nozzle.