CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Trans Cranial Magnetic Stimulationdevice
Likely dose
Not stated in record
Key inclusion· 2
  • Confirmed diagnosis of Autism Spectrum Disorder (ASD) by DSM-5 criteria and Gilliam Asperger Disorder Scale (GADS)
  • Adequate understanding and cooperation for the rTMS procedure
Key exclusion· 4
  • Significant anxiety or contact avoidance that would prevent cooperation with the procedure
  • Known diagnosis of seizures
  • Metallic implants or devices in the head or neck area
  • Pregnancy

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05371912
NCT05371912N/ACompleted

Enhancement of Behavioral and Cognitive Outcomes in Autism Spectrum Disorder Via Neurostimulation

Christiana Care Health Services·interventional·Posted May 12, 2022·Updated Nov 26, 2025

In Brief

A clinical study evaluating Trans Cranial Magnetic Stimulation for Autism Spectrum Disorder. Completed, enrolled 16 participants across 1 site.

Detailed Summary

Autism spectrum disorder (ASD) encompasses a range of limitations in reciprocal social and communicative milestones, as well as restrictive and/or repetitive patterns of behavior which lead to significant functional challenges impacting individuals throughout their lifespan. There are major shortcomings in the existing pharmacological interventions; they are of limited efficacy, target a subset of problematic behaviors, and fail to improve social cognition. To overcome these limitations and improve outcomes, the investigators study the use of neurostimulation to mitigate the social and cognitive manifestations of ASD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedMay 12, 2022
Enrollment StartMar 15, 2022
Primary CompletionOct 31, 2023
Study CompletionFeb 1, 2024
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 4.1 years ago

Interventions

Trans Cranial Magnetic Stimulationdevice

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurostimulation technique that alters cortical excitability by repeated induction of electromagnetic activity. FDA approved for depression, rTMS is a promising tool in the field of neuropsychiatry with an excellent safety profile.