CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 200 enrolled
Drug / intervention
Abrocitinib 100 mg +1 moredrug
Likely dose
Abrocitinib 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05375929
NCT05375929Phase 3Completed

A RANDOMIZED, OPEN-LABEL, PARALLEL-GROUP STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ABROCITINIB 100 MG AND 200 MG TABLETS IN PARTICIPANTS AGED 12 YEARS AND OLDER WITH MODERATE TO SEVERE ATOPIC DERMATITIS IN INDIA

Pfizer·interventional·Posted May 17, 2022·Updated Oct 15, 2024

In Brief

A Phase 3 clinical trial evaluating Abrocitinib 100 mg and Abrocitinib 200 mg for Atopic Dermatitis. Completed, enrolled 200 participants across 15 sites.

Detailed Summary

The purpose of this clinical trial is to learn about the safety and how well the study medicine (called Abrocitinib) works for the potential treatment of moderate to severe Atopic Dermatitis (AD) in India. AD, also known as atopic eczema, is a chronic, relapsing skin condition characterized by dry, itchy skin lesions which can affect any part of the body. Adult peoples who participate in this study will take either 100 mg or 200 mg of abrocitinib tablets by mouth for a duration of 12 weeks and adolescents will take for duration of 52 weeks. Knee Magnetic Resonance Imagine (MRI) will be done on adolescent peoples to determine bone safety findings. We will examine the experiences of people receiving the study medicines. This will help us determine if the study medicines are safe and how well they work.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndia
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedMay 17, 2022
Enrollment StartJul 16, 2022
Primary CompletionJun 9, 2023
Study CompletionMar 14, 2024
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 4.1 years ago

Interventions

Abrocitinib 100 mgdrug

Orally administered, abrocitinib 100 mg tablets QD

Abrocitinib 200 mgdrug

Orally administered, abrocitinib 200 mg tablets QD.