CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 65 enrolled
Drug / intervention
CRAFT-EP +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05380583
NCT05380583N/ACompleted

Treatment Engagement in Families With Substance Use and Psychosis: A Pilot Study

Mclean Hospital·interventional·Posted May 19, 2022·Updated Feb 27, 2026

In Brief

A clinical study evaluating CRAFT-EP and TAU for Psychosis and 10 related conditions. Completed, enrolled 65 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) for families experiencing early psychosis and substance use delivered exclusively or primarily via telehealth (video conferencing).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedMay 19, 2022
Enrollment StartMay 19, 2022
Primary CompletionDec 20, 2024
Study CompletionJan 23, 2026
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 4.1 years ago

Interventions

CRAFT-EPbehavioral

CRAFT-EP is a behavioral intervention delivered via telehealth with the option for one in-person session (when local guidelines allow in-person care without masks). The coaching session topics include self-care, communication, functional analysis, positive reinforcement, treatment engagement, natural consequences, problem solving, and planning next steps. The intervention is designed for families of individuals experiencing psychosis and substance use who are enrolled or seeking enrollment in early psychosis outpatient services. Participants will be asked to complete assessments at pre-, mid- (approximately week 4), post-intervention, and a follow-up assessment approximately 12 weeks post-intervention.

TAUbehavioral

Participants may continue to receive their ongoing treatment, if any, which may include psychosocial and/or pharmacological interventions.