CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 10 enrolled
Drug / intervention
NOMO Protocoldrug
Likely dose
NOMO Protocol 0.5 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05386069
NCT05386069Phase 3Completed

The Effect of a Non-Opioid Multimodal Pain (NOMO) Protocol in Decreasing Narcotic Use After Urogynecologic Surgery

Prisma Health-Upstate·interventional·Posted May 23, 2022·Updated May 23, 2025

In Brief

A Phase 3 clinical trial evaluating NOMO Protocol for Opioid Use. Completed, enrolled 10 participants across 1 site.

Detailed Summary

The objective of this study is to evaluate narcotic use after implementation of a Non-Opioid Multimodal Pain (NOMO) protocol in patients who are undergoing a urogynecologic procedure. The study will also evaluate secondary outcomes, including: post-operative pain rating, length of hospital stay, postoperative antiemetic use, bladder catheterization at discharge, number of post-operative phone calls, and rate of reported side effects of opioid use (nausea/constipation). Study participants will be asked to utilize the validated Brief Pain Inventory (appendix A) scale to assess post-operative pain levels. Based on inpatient post-operative opioid use and number of opioid pills prescribed at discharge, an attempt will be made to develop an algorithm for recommended opioid prescribing patterns.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOpioid Use
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedMay 23, 2022
Enrollment StartNov 15, 2019
Primary CompletionDec 1, 2020
Study CompletionJun 1, 2021
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 4.1 years ago

Interventions

NOMO Protocoldrug

Standard weight-based ketamine bolus (0.5 mg/kg) at procedure start, no Opioid rescue medications