CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 28 enrolled
Drug / intervention
Mindset: Therapist-guided smartphone-delivered CBTbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05386329
NCT05386329N/ACompleted
CompareCT.gov

Development and Preliminary Testing of a Non-regulated Digital Service That Supports Cognitive Behavioral Therapy for Depressive Symptoms Under Clinical Supervision

Massachusetts General Hospital·interventional·Posted May 23, 2022·Updated May 28, 2025

In Brief

A clinical study evaluating Mindset: Therapist-guided smartphone-delivered CBT for Major Depressive Disorder. Completed, enrolled 28 participants across 1 site.

Detailed Summary

We are testing a smartphone app that provides therapy for depression. Participants will also receive short weekly virtual appointments with a therapist. Researchers want to know if this new treatment is usable, whether participants are satisfied with it, and whether it can help lower symptoms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMajor Depressive Disorder
CountriesUnited States
CollaboratorsKoa Health B.V.

Timeline

N/ACompletedFinished
2023202420252026
First PostedMay 23, 2022
Enrollment StartMay 11, 2022
Primary CompletionApr 21, 2023
Study CompletionAug 7, 2023
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 4.1 years ago

Interventions

Mindset: Therapist-guided smartphone-delivered CBTbehavioral

All participants will receive the app-delivered CBT, including modules such as cognitive skills (e.g., cognitive restructuring, core belief work), behavioral skills (e.g., activity scheduling), and mindfulness. Therapists will also conduct brief weekly virtual appointments with participants.