CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 178 enrolled
Drug / intervention
CSF-1 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05393895
NCT05393895Phase 3Completed

A Multi-Center, Double-Masked, Vehicle-Controlled, Evaluation of the Safety of CSF-1 in Presbyopic Subjects

Orasis Pharmaceuticals Ltd.·interventional·Posted May 26, 2022·Updated Jun 11, 2025

In Brief

A Phase 3 clinical trial evaluating CSF-1 and Vehicle for Presbyopia. Completed, enrolled 178 participants across 12 sites.

Detailed Summary

This is a multi-center, double-masked, vehicle-controlled study. The purpose of the study is to evaluate the safety of CSF-1 compared with vehicle in presbyopic subjects. Subjects will be treated for at least 6 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPresbyopia
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedMay 26, 2022
Enrollment StartApr 22, 2022
Primary CompletionDec 1, 2022
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.1 years ago

Interventions

CSF-1drug

One drop bilaterally twice daily for at least 6 weeks

Vehicledrug

One drop bilaterally twice daily for at least 6 weeks