At a glance
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The Role of Periodontal Diseases and Stimulation of Saliva Secretion in the Acute Phase of
In Brief
A clinical study evaluating saliva stimulation for Periodontal Diseases and 2 related conditions. Completed, enrolled 50 participants across 1 site.
Detailed Summary
Methods: 100 consecutive patients with their first ever ischemic stroke were enrolled in the study. 56 randomly selected patients were subjected to stimulation of salivation, the remaining patients were not stimulated. The severity of the neurological condition was assessed using the NIHSS scale on days 1, 3 and 7 of stroke. The incidence of periodontal diseases was classified using the Hall's scale in the 1st day of stroke. On days 1 and 7 of stroke, the concentration of IL-1beta, MMP8, OPG and RANKL in the patients' saliva was assessed using the Elisa technique. At the same time, the level of CRP and the number of leukocytes in the peripheral blood were tested on days 1, 3 and 7 of the stroke, and the incidence of upper respiratory and urinary tract infections was assessed.
Study Details
Timeline
Interventions
In 50 patients with ischemic stroke, saliva was the option of a neurologopedic massage of choice