CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 14 enrolled
Drug / intervention
Midazolam +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05395104
NCT05395104Phase 1Completed

A Phase 1, Open-label, 1-sequence Crossover, Drug-drug Interaction Study to Assess the Effect of Repeated Doses of Cefiderocol on the Pharmacokinetics of Midazolam in Healthy Adult Participants

Shionogi·interventional·Posted May 27, 2022·Updated Dec 14, 2023

In Brief

A Phase 1 clinical trial evaluating Midazolam and Cefiderocol for Healthy Volunteers. Completed, enrolled 14 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the effect of repeated doses of cefiderocol on the PK of midazolam.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
2023202420252026
First PostedMay 27, 2022
Enrollment StartMay 24, 2022
Primary CompletionJul 13, 2022
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 4.1 years ago

Interventions

Midazolamdrug

Syrup for oral administration

Cefiderocoldrug

Liquid for intravenous infusion