CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 31 enrolled
Drug / intervention
Solar Simulated Light (SSL)other
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05398237
NCT05398237N/ACompleted
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An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light

University of Arizona·interventional·Posted May 31, 2022·Updated Sep 24, 2024

In Brief

A clinical study evaluating Solar Simulated Light (SSL) for Sun Damaged Skin. Completed, enrolled 31 participants across 1 site.

Detailed Summary

The purpose of this project is to obtain clinical data, including skin samples, that will help investigators evaluate changes occurring in sun damaged human skin as a result of light that simulates sun exposure (Solar Simulated Light). Of specific interest are the molecular targets for cancer prevention. Molecular targets are the parts of the body's cells that have been shown to play a role in causing or preventing cancer and which scientists seek to affect in a way that may slow or eliminate the development of cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSun Damaged Skin
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedMay 31, 2022
Enrollment StartFeb 3, 2020
Primary CompletionAug 1, 2023
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 4.1 years ago

Interventions

Solar Simulated Light (SSL)other

Acute SSL will be delivered to sun damaged skin at a rate of two-times the minimal erythema dose of each individual subject. Minimal erythema dose is defined as the smallest dose of energy necessary to produce confluent erythema with four distinct borders at 22-26 hours post-exposure.