At a glance
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Double-Blind, Randomised Placebo-Controlled Study to Determine the Effect of Beetroot Juice on Reducing Blood Pressure in Hypertensive Adults With Autosomal Dominant Polycystic Kidney Disease
In Brief
A clinical study evaluating Beetroot juice and Nitrate-depleted beetroot juice for Autosomal Dominant Polycystic Kidney and 2 related conditions. Completed, enrolled 60 participants across 2 sites.
Detailed Summary
People with autosomal dominant polycystic kidney disease (ADPKD) develop high blood pressure and kidney disease. Previous studies have shown that a commonly occurring chemical, nitric oxide (NO), is reduced in ADPKD, and may contribute, in part, to high blood pressure in this condition. Nitrate is found in high concentrations naturally in beetroots, and increases NO. The aim of this study is to determine if beetroot juice reduces blood pressure in hypertensive people with ADPKD.
Study Details
Timeline
Interventions
70mls beetroot juice (400mg nitrate) given daily for 4 weeks
70mls beetroot juice (nitrate-depleted) given daily for 4 weeks