CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 644 enrolled
Drug / intervention
K-161 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05403827
NCT05403827Phase 3Completed

A Phase 3, Prospective, Double-masked, Randomized, Multi-center, Vehicle-controlled, Parallel-group, 12-week Administration and 40-week Extension Study Confirming the Efficacy and Safety of K-161 Ophthalmic Solution for the Treatment of Moderate to Severe Dry Eye Disease

Kowa Research Institute, Inc.·interventional·Posted Jun 3, 2022·Updated Jan 14, 2025

In Brief

A Phase 3 clinical trial evaluating K-161 and Placebo for Dry Eye Disease. Completed, enrolled 644 participants across 51 sites.

Detailed Summary

The purpose of this study is to assess the efficacy and safety of K-161 ophthalmic solution for the treatment of moderate to severe dry eye disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDry Eye Disease
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedJun 3, 2022
Enrollment StartJul 3, 2022
Primary CompletionAug 25, 2023
Study CompletionDec 5, 2023
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 4.1 years ago

Interventions

K-161drug

K-161 Ophthalmic Solution

Placebodrug

Vehicle Solution