CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 232 enrolled
Drug / intervention
SI-614 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05411367
NCT05411367Phase 3Completed

A Multicenter, Randomized, Double-masked and Placebo-controlled Study Evaluating the Efficacy and Safety of SI-614 Ophthalmic Solution in Patients With Dry Eye

Seikagaku Corporation·interventional·Posted Jun 9, 2022·Updated Jan 16, 2026

In Brief

A Phase 3 clinical trial evaluating SI-614 and Placebo for Dry Eye Disease. Completed, enrolled 232 participants across 6 sites.

Detailed Summary

The purpose of this study is to evaluate the efficacy and safety of SI-614 ophthalmic solution compared with placebo in patients with dry eye

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDry Eye Disease
CountriesUnited States

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedJun 9, 2022
Enrollment StartJul 28, 2022
Primary CompletionMar 2, 2023
Study CompletionApr 27, 2023
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.1 years ago

Interventions

SI-614drug

One drop of study drug was instilled in each eye 4 times daily for 84 days

Placebodrug

One drop of study drug was instilled in each eye 4 times daily for 84 days