At a glance
ClinicalIndex Comparison RecordN/ACompleted· 180 enrolled
Drug / intervention
5 Fluorouracil (5 FU) Cream +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV
In Brief
A clinical study evaluating 5 Fluorouracil (5 FU) Cream and Placebo for Cervical Cancer and 4 related conditions. Completed, enrolled 180 participants across 1 site.
Detailed Summary
The purpose of this study is to explore whether an anti-cancer medication (5-fluorouracil cream) placed in the vagina after a surgical excision procedure is an acceptable and useful form of treatment for cervical precancer among the woman with HIV infection.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCervical Cancer, CIN2, CIN3, Human Immunodeficiency Virus, Human Papillomavirus
CountriesSouth Africa
CollaboratorsNational Cancer Institute (NCI)
Timeline
N/ACompletedFinished
2023202420252026
First PostedJun 2022
Enrollment StartMar 2023
Primary CompletionJun 2025
TodayJul 2026
First PostedJun 10, 2022
Enrollment StartMar 22, 2023
Primary CompletionJun 30, 2025
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 4.1 years ago
Interventions
5 Fluorouracil (5 FU) Creamdrug
Intravaginal topical chemotherapy, 5-fluorouracil cream
Placebodrug
Intravaginal topical placebo cream