CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 31 enrolled
Drug / intervention
Tamsulosin +1 moredrug
Likely dose
Tamsulosin dosing per standard use; matching placebo for 12 weeks in randomized orderAI-extracted
Key inclusion· 7
  • Male, age 55-80 years at screening
  • Currently taking tamsulosin for urinary symptoms for ≥12 months
  • International Prostate Symptom Score 5-25
  • Owns Android or iPhone smartphone, tablet, or computer with home WiFi access
Key exclusion· 5
  • Taking tamsulosin for less than 12 months
  • IPSS <5 or >25
  • Currently enrolled in another mobile app-based clinical study
  • Planning to relocate during study duration

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05415748
NCT05415748Phase 4Completed

PlacEbo-controlled, Randomized, Patient-Selected Outcomes N-of-1 triALs (PERSONAL-pilot): Alpha-blockers for Lower Urinary Tract Symptoms

University of California, San Francisco·interventional·Posted Jun 13, 2022·Updated Aug 22, 2025

In Brief

A Phase 4 clinical trial evaluating Tamsulosin and Placebo for Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms. Completed, enrolled 31 participants across 1 site.

Detailed Summary

This is a pilot 12-week randomized, placebo-controlled N-of-1 deprescribing trial among older men receiving chronic tamsulosin therapy for lower urinary tract symptoms attributed to benign prostatic hyperplasia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedJun 13, 2022
Enrollment StartSep 18, 2021
Primary CompletionJul 22, 2022
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 4.1 years ago

Interventions

Tamsulosindrug

Tamsulosin and matching placebo to be taken in a randomized order for 12 weeks

Placebodrug

Tamsulosin and matching placebo to be taken in a randomized order for 12 weeks