CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 36 enrolled
Drug / intervention
trans-cutaneous auricular sensory stimulationdevice
Likely dose
Transcutaneous auricular sensory stimulation (device-based intervention; specific stimulation parameters not detailed)AI-extracted
Key inclusion· 2
  • ✓Acute ischemic stroke requiring mechanical thrombectomy (under general anesthesia or sedation)
  • ✓Hypertension on admission: systolic BP >140 mmHg and/or diastolic BP >80 mmHg
Key exclusion· 4
  • ✕Concurrent participation in another clinical trial with a similar biological mechanism
  • ✕Prior enrollment in the VANS trial
  • ✕Anatomical or other contraindication to transcutaneous auricular sensory stimulation
  • ✕Pregnancy

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05417009
NCT05417009N/ACompleted
CompareCT.gov

Vagal Autonomic Neuromodulation by Transcutaneous Nerve Stimulation in Acute Ischaemic Stroke Requiring Mechanical Thrombectomy.

Queen Mary University of London·interventional·Posted Jun 14, 2022·Updated Jul 14, 2025

In Brief

A clinical study evaluating trans-cutaneous auricular sensory stimulation for Ischemic Stroke and 3 related conditions. Completed, enrolled 36 participants across 1 site.

Detailed Summary

Autonomic modulation by transcutaneous vagal nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: a phase IIa, sham controlled randomised trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIschemic Stroke, Thrombotic Stroke, Autonomic Dysfunction, Autonomic Imbalance
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJun 14, 2022
Enrollment StartApr 26, 2023
Primary CompletionJul 21, 2023
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 4.0 years ago

Interventions

trans-cutaneous auricular sensory stimulationdevice

Transcutaneous auricular sensory stimulation