CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 91 enrolled
Drug / intervention
CCH-aaes +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05419505
NCT05419505Phase 2Completed

APHRODITE-1: A Phase 2, Open Label, Self-Controlled Study of Different Interventions to Reduce Bruising Following CCH-Aaes Treatment for Cellulite of the Buttocks in Adult Females

Endo Pharmaceuticals·interventional·Posted Jun 15, 2022·Updated Mar 7, 2025

In Brief

A Phase 2 clinical trial evaluating CCH-aaes and Antifibrinolytic Agent for Edematous Fibrosclerotic Panniculopathy and Cellulite. Completed, enrolled 91 participants across 13 sites.

Detailed Summary

The study will evaluate the effect of different doses, strengths (concentrations), diluent additives, depths of injection, and methods of injection on the severity of bruising potentially induced by QWO (collagenase clostridium histolyticum-aaes \[CCH-aaes\]).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedJun 15, 2022
Enrollment StartJun 15, 2022
Primary CompletionJan 3, 2023
Study CompletionJun 21, 2023
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.0 years ago

Interventions

CCH-aaesdrug

Administered by subcutaneous injection.

Antifibrinolytic Agentdrug

Self-administered by participants enrolled in Cohort 7.