CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Osteogen plug® +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05419778
NCT05419778N/ACompleted

Clinical Evaluation Of Soft Tissue Closure In Alveolar Ridge Preservation Procedures

University of Tennessee·observational·Posted Jun 15, 2022·Updated Jul 8, 2022

In Brief

An observational study evaluating Osteogen plug® and MInerOss® for Alveolar Ridge Preservation. Completed, enrolled 14 participants across 1 site.

Detailed Summary

Tooth loss is accompanied by different patterns of bone loss. Up to 50% loss of alveolar crestal bone width will likely occur 1 year after tooth loss, especially in the anterior maxilla. A great percentage of the process of alveolar bone resorption occurs within the first 3 to 6 months post-extraction. If ridge preservation is not conducted, 40%-60% of the total alveolar bone volume is lost during the first 2-3 years post-extraction, and this phenomenon has shown to continue to occur at a rate of 0.25%-0.5% loss per year. It has been proposed that ridge augmentation procedures may reduce the expected ridge reduction after tooth loss. Ridge augmentation procedures may require the use of bone grafts and non-resorbable or non-resorbable barrier membranes. The use of non-resorbable barrier membranes for ridge augmentation has the clinical disadvantage of needing a second procedure for its removal during the healing phase. Osteogen® plug (OPP) consists of a non-ceramic bone graft incorporated in type I bovine Achilles tendon collagen. OPP was first developed to serve as a one-step grafting solution for ridge preservation without the need for a barrier membrane

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJun 15, 2022
Enrollment StartFeb 8, 2019
Primary CompletionJan 6, 2021
Study CompletionJan 11, 2021
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 4.0 years ago

Interventions

Osteogen plug®device

A type I bovine Achilles tendon collagen with bioactive resorbable calcium apatite crystals (CCAC)

MInerOss®device

A cortico-cancellous bone chips mix with polytetrafluoroethylene (dPTFE)(Cytoplast) barrier membrane.