CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 25 enrolled
Drug / intervention
Soterix 1x1 tDCS mini CT +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05419999
NCT05419999N/ACompleted

Safety, Feasibility, and Benefits of Transcranial Direct Current Stimulation (tDCS) in Human Subjects With Posttraumatic Stress Disorder (PTSD) Receiving an Exposure-based, Behavioral Therapy

The University of Texas Health Science Center at San Antonio·interventional·Posted Jun 15, 2022·Updated May 29, 2025

In Brief

A clinical study evaluating Soterix 1x1 tDCS mini CT, Sham Soterix 1x1 tDCS Mini CT, and 1 other intervention for Post Traumatic Stress Disorder. Completed, enrolled 25 participants across 1 site.

Detailed Summary

The primary objective of this study is to evaluate the safety, feasibility, and psychological and physiological treatment benefits of transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique, when delivered in combination with Written Exposure Therapy (WET), for posttraumatic stress disorder posttraumatic stress disorder (PTSD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJun 15, 2022
Enrollment StartJan 9, 2023
Primary CompletionApr 25, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 4.0 years ago

Interventions

Soterix 1x1 tDCS mini CTdevice

During stimulation, a current flows between the electrodes passing through the brain to complete the circuit. tDCS is hypothesized to modulate intrinsic neuronal activity by enhancing neuronal resting potential, or altering the likelihood that a neuron will (or will not) depolarize.

Sham Soterix 1x1 tDCS Mini CTother

Sham setting is used on the Soterix transcranial electrical stimulator

Written Exposure Therapy (WET)behavioral

An exposure-based, behavioral psychotherapy for PTSD.