CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 49 enrolled
Drug / intervention
Non-intubated Laryngomicrosurgeryprocedure
Likely dose
Not stated in record
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Search/NCT05420649
NCT05420649N/ACompleted

Evaluation of the Feasibility and Safety of Laryngoscopic Microsurgery Under Non-intubation Anesthesia With Combination of Superior Laryngeal Nerve Block

Kaohsiung Veterans General Hospital.·interventional·Posted Jun 15, 2022·Updated Oct 27, 2023

In Brief

A clinical study evaluating Non-intubated Laryngomicrosurgery for Spontaneous Breathing and 2 related conditions. Completed, enrolled 49 participants across 1 site.

Detailed Summary

Nonintubated anesthesia applied in combination with high-flow nasal oxygen (HFNO) is an alternative strategy for laryngeal microsurgery (LMS). LMS is a common procedure in otolaryngology that typically requires endotracheal tube intubation under general anesthesia. Endotracheal tube intubation causes complications; a nonintubated strategy can avoid these complications and provide a clearer surgical field of vision, enabling vocal cord inspection and disposal. Administering a muscle relaxant can also help prevent bucking during surgery but can engender apnea and hypercapnia, which may have negative effects on hemodynamics. Therefore, the investigators assessed the effectiveness of a superior laryngeal nerve block (SLNB) with intravenous general anesthesia in maintaining spontaneous breathing and improving safety during LMS with nonintubated anesthesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTaiwan
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJun 15, 2022
Enrollment StartOct 20, 2020
Primary CompletionOct 26, 2022
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 4.0 years ago

Interventions

Non-intubated Laryngomicrosurgeryprocedure

Non-intubated LMS was performed with assistance of Optiflow (HFNO).