CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 74 enrolled
Drug / intervention
Routine Medical Treatment +2 moreother
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05422235
NCT05422235N/ACompleted

Comparison of the Effects of Different Exercise Programs on Lower Extremity Distal Tissue Mechanics, Muscle Strength and Neuropathy Symptoms in Type 2 Diabetics With Peripheral Neuropathy

Eastern Mediterranean University·interventional·Posted Jun 16, 2022·Updated Apr 6, 2026

In Brief

A clinical study evaluating Routine Medical Treatment, Aerobic Exercise, and 1 other intervention for Diabetic Foot and Peripheral Neuropathy With Type 2 Diabetes. Completed, enrolled 74 participants across 1 site.

Detailed Summary

To examine the effects of aerobic exercise and foot exercises in addition to aerobic exercise on lower extremity distal tissue mechanics, muscle strength and neuropathy symptoms in type 2 diabetics with peripheral neuropathy. Subjects will be divided into three groups through randomization.Subjects in the 1st group will be included in the control group and will continue their routine medical treatment for 12 weeks. Subjects in the 2nd group, in addition to their medical treatment, only aerobic exercise training,subjects in the 3rd group will be given aerobic exercise training and exercises for the foot and ankle in addition to their medical treatment. After 12 weeks of training, subjects will be followed for another 12 weeks. subjects will be evaluated before treatment, at 12 and 24 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJun 16, 2022
Enrollment StartNov 12, 2022
Primary CompletionFeb 28, 2025
Study CompletionMar 1, 2025
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 4.0 years ago

Interventions

Routine Medical Treatmentother

Subjects will continue their routine medical treatment.

Aerobic Exerciseother

Symptom-limited peak heart rates of subjects will be determined using the modified Bruce Protocol. For aerobic training, subject will be carried out on the treadmill according to the results of exercise tests. Initially, 40-60% of the peak heart rate will be trained and progression will be made in subject training programs every 2 weeks. Training will consist of warm-up, main exercise and cool-down periods. Aerobic training will be done 3 days a week for 12 weeks. Subjects will be followed for 24 weeks. The room temperature will be fixed at 25°C in order to keep the impact of environmental factors at a minimum. In addition, individuals will be asked to come with appropriate shoes and clothes for the training.

Aerobic Exercise+ Foot-Related Exerciseother

In addition to walking training specific to the subject in the aerobic exercise group, special exercises will be given to the feet and ankles. These exercises will be aimed at stretching, strengthening, increasing sensory input. Treatment program will be done 3 days a week for 12 weeks. Subjects will be followed for 24 weeks.