At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals
In Brief
A clinical study evaluating Intermittent hypoxia and Intermittent normoxia for Intermittent Hypoxia. Completed, enrolled 41 participants across 1 site.
Detailed Summary
The objective of the present study is to determine whether intermittent hypoxia protects against ischemia-reperfusion injury in young and older healthy individuals. The investigators hypothesize that intermittent hypoxia will attenuate the reduction in flow-mediated dilation following ischemia-reperfusion injury.
Study Details
Timeline
Interventions
The intermittent hypoxia protocol will consist of three 4-minute hypoxic cycles (arterial oxygen saturation of 80%) interspersed with 4-minute normoxic cycles.
The intermittent normoxia protocol will consist of three 4-minute normoxic cycles (compressed air) interspersed with 4-minute normoxic cycles (room air).