CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
White Wine +1 moreother
Likely dose
White wine: 5 ounces daily for 3 weeks or white grape juice: 6 ounces daily for 3 weeksAI-extracted
Key inclusion· 6
  • ✓ER+ breast cancer diagnosis
  • ✓Female sex at birth
  • ✓Postmenopausal status (natural or induced)
  • ✓Current aromatase inhibitor therapy (anastrozole, letrozole, or exemestane)
Key exclusion· 6
  • ✕Heavy alcohol consumption (>1 drink/day) or alcohol abuse (AUDIT≥8) or ≥4 drinks in one day within last 6 months
  • ✕Cytotoxic chemotherapy or radiation currently or planned within 2 months
  • ✕Any surgery planned in the next 2 months
  • ✕Alcohol flushing syndrome

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05423730
NCT05423730N/ACompleted
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Effect of Light Alcohol Intake on Sex Hormone Levels Among Postmenopausal Women With ER+ Breast Cancer on Aromatase Inhibitor Therapy: The Alcohol and Breast Cancer (ABC) Trial

Beth Israel Deaconess Medical Center·interventional·Posted Jun 21, 2022·Updated Dec 20, 2024

In Brief

A clinical study evaluating White Wine and Grape Juice for ER+ Breast Cancer and 2 related conditions. Completed, enrolled 23 participants across 1 site.

Detailed Summary

This research study is a pilot study, which is the first time investigators are examining the effect of light alcohol consumption on sex hormones among postmenopausal women with estrogen receptor-positive (ER+) breast cancer taking an aromatase inhibitor The names of the study exposures involved in this study are: * White wine * White grape juice

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsER+ Breast Cancer, Breast Cancer, Aromatase Inhibitors
CountriesUnited States
CollaboratorsNational Institute on Alcohol Abuse and Alcoholism (NIAAA), Dana-Farber Cancer Institute

Timeline

N/ACompletedFinished
2023202420252026
First PostedJun 21, 2022
Enrollment StartSep 1, 2022
Primary CompletionJul 31, 2023
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 4.0 years ago

Interventions

White Wineother

One serving (5 ounces) of white wine daily for 3 weeks

Grape Juiceother

One serving (6 ounces) of white grape juice daily for 3 weeks