CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 22 enrolled
Drug / intervention
methadone hydrochloride 0.1mg/kgdrug
Likely dose
methadone hydrochloride 0.1mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05425420
NCT05425420Phase 2Completed
CompareCT.gov

Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose Intravenous Methadone in Healthy Adult Volunteers (MTH02)

Kanecia Obie Zimmerman·interventional·Posted Jun 21, 2022·Updated Feb 10, 2025

In Brief

A Phase 2 clinical trial evaluating methadone hydrochloride 0.1mg/kg for Pain, Postoperative. Completed, enrolled 22 participants across 1 site.

Detailed Summary

Single-center, open label, single-session study to evaluate methadone pharmacokinetics and pharmacodynamic in adults.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedJun 21, 2022
Enrollment StartAug 11, 2023
Primary CompletionJan 20, 2024
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 4.0 years ago

Interventions

methadone hydrochloride 0.1mg/kgdrug

Single dose of methadone hydrochloride administered via intravenous (IV)