CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 195 enrolled
Drug / intervention
CIN-107 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05432167
NCT05432167Phase 2Completed

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group, Dose-Ranging Study to Evaluate CIN-107 for the Treatment of Patients With Uncontrolled Hypertension and Chronic Kidney Disease

AstraZeneca·interventional·Posted Jun 27, 2022·Updated May 20, 2025

In Brief

A Phase 2 clinical trial evaluating CIN-107 and Placebo for Uncontrolled Hypertension and Chronic Kidney Diseases. Completed, enrolled 195 participants across 71 sites.

Detailed Summary

This study will evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney Disease (CKD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsParexel

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedJun 27, 2022
Enrollment StartApr 29, 2022
Primary CompletionMay 2, 2024
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 4.0 years ago

Interventions

CIN-107drug

Patients will take CIN-107 tablets by mouth once daily.

Placebodrug

Patients will take placebo tablets by mouth once daily.