CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
Transcranial Direct Current Stimulationdevice
Likely dose
tDCS 2mA in 30-minute sessions: 5 sessions per week for 3 weeks, then 2 sessions per week for 3 weeksAI-extracted
Key inclusion· 3
  • Confirmed bipolar disorder diagnosis per DSM-5
  • Depression severity ≥18 on MADRS (Montgomery-Åsberg Depression Rating Scale)
  • Currently on stable mood-stabilizing medication for ≥2 weeks
Key exclusion· 4
  • Any comorbid psychiatric disorder
  • Significant risk of suicide or self-harm
  • Any contraindication to tDCS, including implanted electronic medical devices
  • History of epilepsy

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05436613
NCT05436613N/ACompleted

Community-based Transcranial Direct Current Stimulation Treatment for Bipolar Depression

University of East London·interventional·Posted Jun 29, 2022·Updated Aug 14, 2025

In Brief

A clinical study evaluating Transcranial Direct Current Stimulation for Depression, Bipolar and 3 related conditions. Completed, enrolled 44 participants across 1 site.

Detailed Summary

Bipolar disorder is a severe and disabling disorder. The course of illness is often progressive but is highly heterogeneous between individuals and within the lifetime for an individual. The most common treatments are medications. However, for many individuals, combinations of medications are often required, and full recovery is infrequent. The novel brain stimulation treatment, transcranial direct current stimulation (tDCS), is a potential first-line treatment for bipolar depression. The present research question is whether tDCS can be provided as a home-based treatment for bipolar depression for adults with bipolar disorder.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom

Timeline

N/ACompletedFinished
2023202420252026
First PostedJun 29, 2022
Enrollment StartMay 1, 2022
Primary CompletionMay 30, 2024
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 4.0 years ago

Interventions

Transcranial Direct Current Stimulationdevice

tDCS at 2mA in 30 minute sessions for 5 sessions per week for 3 weeks and then 2 sessions per week for 3 weeks.