CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 147 enrolled
Drug / intervention
Melatonin +1 moredrug
Likely dose
Melatonin 2 mg daily for 4 weeksAI-extracted
Key inclusion· 3
  • Children aged 1–18 years
  • Confirmed diagnosis of epilepsy
  • Sleep problems
Key exclusion· 5
  • Bedridden with limited mobility
  • Liver or kidney dysfunction
  • Recent use of hypnotics, antidepressants, or anxiolytics within 4 weeks
  • Pregnant or breastfeeding (adolescent girls)

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05439876
NCT05439876Phase 3Completed

Getting SMART for Pediatric Epilepsy (Sleep, Melatonin, and Research Trial, SMART)

National Taiwan University Hospital·interventional·Posted Jun 30, 2022·Updated Aug 29, 2025

In Brief

A Phase 3 clinical trial evaluating Melatonin and Placebo for Epilepsy in Children. Completed, enrolled 147 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the effect of melatonin for improving sleep in pediatric epilepsy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTaiwan
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedJun 30, 2022
Enrollment StartJul 18, 2022
Primary CompletionJan 3, 2025
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 4.0 years ago

Interventions

Melatonindrug

Melatonin 2 mg daily for 4 weeks

Placebodrug

Placebo daily for 4 weeks