CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 107 enrolled
Drug / intervention
Tranexamic acid injection +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05441592
NCT05441592Phase 4Completed

A Randomized Control Trial Assessing the Effect of Topical Tranexamic Acid on Risk of Hematoma in Breast Surgery

University of Michigan·interventional·Posted Jul 1, 2022·Updated Nov 26, 2025

In Brief

A Phase 4 clinical trial evaluating Tranexamic acid injection and No additional irrigation for Hematoma Postoperative. Completed, enrolled 107 participants across 1 site.

Detailed Summary

This trial is being completed to evaluate the safety and efficacy of topical tranexamic acid use in preventing hematomas in routine breast plastic surgery operations.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedJul 1, 2022
Enrollment StartAug 15, 2022
Primary CompletionOct 22, 2024
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 4.0 years ago

Interventions

Tranexamic acid injectiondrug

The breast pockets will additionally be irrigated with 150 cc of 2.67% TXA (75 cc in each breast). The TXA solution will be allowed to be sit in the breast pocket for 15 minutes and then removed after 15 minutes.

No additional irrigationother

There will be no additional irrigation after the standard surgical procedure.