CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 92 enrolled
Drug / intervention
Music and Theta Auditory Beat Stimulation +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05442086
NCT05442086N/ACompleted

Music and Auditory Beat Stimulation and Its Effect on Anxiety

Toronto Metropolitan University·interventional·Posted Jul 1, 2022·Updated Oct 3, 2025

In Brief

A clinical study evaluating Music and Theta Auditory Beat Stimulation and Pink Noise (control) for Anxiety State. Completed, enrolled 92 participants across 1 site.

Detailed Summary

Anxiety is a growing problem and has been steadily increasing, particularly in the adolescent and young adult populations in the past 24 years. Music and auditory beat stimulation (ABS) in the theta frequency range (4-7 Hz) are sound-based anxiety treatments that have been investigated in prior studies with subjective measures of anxiety. Here, the anxiety-reducing potential of calm music combined with theta ABS will be examined in a large sample of participants with objective psychophysiological measures (heart rate variability and EEG), stress hormone measures (salivary cortisol) along with subjective measures (STICSA state). Participants with a GAD-2 score of 1 or higher (indicating generalized anxiety) will be randomly assigned to a single 24-27 minute session of sound-based treatment: combined (music \& ABS), or pink noise (control). Pre- and post-intervention heart rate variability and EEG band power (alpha, beta, delta, and theta bands), salivary cortisol, along with somatic and cognitive state anxiety measures (STICSA State) will be collected along with trait anxiety (STICSA Trait), and music absorption (Absorption in Music Scale). The investigators predict that the music \& ABS condition will have significantly increased power in the theta and alpha bands, higher heart rate variability, higher state anxiety reduction, and lower salivary cortisol levels compared to the pink noise control condition.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnxiety State
CountriesCanada
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJul 1, 2022
Enrollment StartAug 10, 2024
Primary CompletionAug 1, 2025
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 4.0 years ago

Interventions

Music and Theta Auditory Beat Stimulationbehavioral

Participants will listen to calm music with theta auditory beat stimulation for 24-27 minutes

Pink Noise (control)behavioral

Participants will listen to pink noise for 24 minutes