At a glance
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Apneic Oxygenation to Prevent Oxygen Desaturation During Intubation in the NICU
In Brief
A clinical study evaluating Apneic Oxygenation and Standard of Care for Neonatal Respiratory Failure and Tracheal Intubation Morbidity. Completed, enrolled 110 participants across 1 site.
Detailed Summary
Tracheal intubation in the NICU is frequently complicated by severe oxygen desaturation. Apneic oxygenation, a method of applying free flowing oxygen via nasal cannula to apneic patients undergoing intubation, prevents or delays oxygen desaturation during intubation in adults and older children. We propose to enroll patients at two sites (Hospital of the University of Pennsylvania and Children's Hospital of Philadelphia) in a randomized trial in infants undergoing intubation in the NICU to determine if apneic oxygenation, compared with no respiratory support or oxygen during laryngoscopy and intubation attempts (standard care), reduces the magnitude of oxygen desaturation during tracheal intubation encounters.
Study Details
Timeline
Arms & Interventions
Interventions
Nasal cannula at a rate of 6L/min with 100% FiO2 during laryngoscopy and intubation attempt(s)
No respiratory support during laryngoscopy and intubation attempt(s) (current standard of care)