CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Tandem t:slim X2 insulin pump: Extended bolus of insulin then standard bolus of insulin +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05454891
NCT05454891N/ACompleted
CompareCT.gov

Postprandial Glucose Control Using an Extended Bolus for High-fat High Protein Meals in a Closed-loop System in Patients With Type 1 Diabetes

University of California, San Francisco·interventional·Posted Jul 12, 2022·Updated May 12, 2026

In Brief

A clinical study evaluating Tandem t:slim X2 insulin pump: Extended bolus of insulin then standard bolus of insulin and Tandem t:slim X2 insulin pump: Standard bolus of insulin then extended bolus of insulin for Type 1 Diabetes. Completed, enrolled 30 participants across 1 site.

Detailed Summary

This study aims to evaluate whether the use of an extended bolus will improve glucose control with high-fat high protein meals using a closed-loop system. The new knowledge gained from this study may provide a method to allow for the proper administration of insulin over an extended period to mitigate the risk of prolonged hyperglycemia or early hypoglycemia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 1 Diabetes
CountriesUnited States
CollaboratorsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Timeline

N/ACompletedFinished
2023202420252026
First PostedJul 12, 2022
Enrollment StartJul 15, 2022
Primary CompletionDec 19, 2024
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 4.0 years ago

Interventions

Tandem t:slim X2 insulin pump: Extended bolus of insulin then standard bolus of insulindevice

For a standardized HFHP breakfast, participants will receive an extended meal bolus of insulin on the first morning and a standard meal bolus of insulin on the second morning of the study.

Tandem t:slim X2 insulin pump: Standard bolus of insulin then extended bolus of insulindevice

For a standardized HFHP breakfast, participants will receive a standard bolus of insulin on the first morning and an extended bolus of insulin on the second morning of the study.